Medicinal mushrooms:Flammulina velutipes creates asparaginase. Agaricus creates conjugated linoleic acid.
BMS manufactures paclitaxel using Penicillium raistrickii and plant cell fermentation (PCF). Endophytic fungi can synthesize podophyllotoxin and camptothecin, precursors to etoposide, teniposide, topotecan, and irinotecan.
Lentinan, PSK, and PSP, are registered anticancer immunologic adjuvants in certain countries.
Irofulven and acylfulvene are anticancer derivatives of illudin S. Clavariadelphus truncatus creates the FTI clavaric acid. Inonotus obliquus creates the betulinic acid precursor betulin.
The pleuromutilin antibiotics are derivatives of the mushroom isolate pleuromutilin. The mushroom isolates lentinan, PSK, and PSP, are licensed pharmaceuticals in certain countries. Fungi that do not produce mushrooms, are currently being used to manufacture paclitaxel, and were the original source of the first beta-lactam antibiotics, statins, immunosuppressants like ciclosporin, and antifungals like griseofulvin.Medicinal mushrooms are mushrooms used or studied as possible treatments for disease. Research indicates mushrooms have potential antiviral, antimicrobial, anticancer, antihyperglycemic, hypocholesterolemic, and anti-inflammatory activities.